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pentobarbital will decrease the level or result of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will lessen the extent or outcome of guanfacine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Potent or moderate CYP3A4 inducers drastically minimize gua